Journal: Malaria Journal

Article Title: An automated haematology analyzer XN-30 distinguishes developmental stages of falciparum malaria parasite cultured in vitro

doi: 10.1186/s12936-018-2208-6

Figure Lengend Snippet: Comparison of parasitaemias for each developmental stage acquired from the XN-30 analyzer and microscopy. a Total iRBCs, b ring-form, c trophozoite, and d schizont of K1 strain. Data represents a summary of 50 biological repeats. R indicates the coefficient of determination. The diagonal line represents the regression line. All data from the XN-30 analyzer and microscopy are provided in Additional file : Table S5

Article Snippet: The automated haematology analyzer XN-30 (Sysmex, Kobe, Japan) has been developed to provide an effective, accurate detection and quantification of infected red blood cells (iRBCs) in human blood samples.

Techniques: Microscopy

Journal: Malaria Journal

Article Title: An automated haematology analyzer XN-30 distinguishes developmental stages of falciparum malaria parasite cultured in vitro

doi: 10.1186/s12936-018-2208-6

Figure Lengend Snippet: Sequential analysis of 3D7 strain after ring-form synchronization. a Typical M scattergrams. b Line graph of MI-RBC%. “$” indicates the time-point taken for comparison of parasitaemia in ( c ). Abbreviations are: RNG, ring-form; TRPZ, trophozoite; and SCHZ, schizont. c Bar graph of MI-RBC% and parasitaemia (%). “X” and “M” indicate the XN-30 analyzer and microscopy, respectively. Red, ring-forms; orange, trophozoites; and purple, schizonts. Results in b and c are expressed as mean ± SD from three independent dishes. All data from the XN-30 analyzer are provided in Additional file : Table S6

Article Snippet: The automated haematology analyzer XN-30 (Sysmex, Kobe, Japan) has been developed to provide an effective, accurate detection and quantification of infected red blood cells (iRBCs) in human blood samples.

Techniques: Microscopy

Journal: Malaria Journal

Article Title: An automated haematology analyzer XN-30 distinguishes developmental stages of falciparum malaria parasite cultured in vitro

doi: 10.1186/s12936-018-2208-6

Figure Lengend Snippet: Representative data from the XN-30 analyzer. a Detection of ring-forms, trophozoites, and schizonts of the 3D7 strain. (i) Typical M and M(SSC-FSC) scattergrams. (ii) Parasitaemias of total and each developmental stages. Original data reported from the XN-30 analyzer are provided in Additional file : Table S1. b Detection of merozoites of K1 strain. (i) Typical M and M(SSC-FSC) scattergrams. Arrows indicate merozoites. (ii) Count of merozoites (upper panel) and parasitaemia of total iRBCs (lower panel). Original data reported from the XN-30 analyzer are provided in Additional file : Table S2. c Detection of gametocytes of 3D7 strain. (i) Typical M and M(SSC-FSC) scattergrams. Arrows and arrowheads indicate mature gametocytes and iRBCs that did not develop to gametocytes and early gametocytes, respectively. (ii) Counts of total and each developmental stages. Original data reported from the XN-30 analyzer are provided in Additional file : Table S4. Red, ring-forms; orange, trophozoites; purple, schizonts; yellow, merozoites; and blue, polychromatic RBCs. These experiments were performed in at least triplicate, and representative data are shown

Article Snippet: The automated haematology analyzer XN-30 (Sysmex, Kobe, Japan) has been developed to provide an effective, accurate detection and quantification of infected red blood cells (iRBCs) in human blood samples.

Techniques: